Application of titanium-based artificial heart thrombus - "Tantalum membrane improves the thrombosis resistance of titanium-based artificial heart"

Figure 1 (A) Thrombosis around the heart valve frame and struts. (B) Fibrin formation. (C) Fibrin forms a thrombus.

Figure 2 Schematic diagram of medical device-related thrombosis

The initial protein adsorption on the implant surface mediates all subsequent phenomena.

Figure 3 Adhesion and activation of platelets on the surface of biomaterials

Table 1 Hemocompatibility test

Fig. 4 Optical images of platelet aggregation on steel surfaces with different coatings 

(a) initial titanium, (b) tantalum, (c) tantalum oxide, d) tantalum nitride, (e) tantalum oxynitride

 Fig.5 AFM images of platelet aggregation on steel surfaces with different coatings

(a) initial titanium, (b) tantalum, (c) tantalum oxide, d) tantalum nitride, (e) tantalum oxynitride